year 1, Issue 2 (6-2015)                   jicr 2015, 1(2): 67-71 | Back to browse issues page

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Ebrahimi M, Khansari-nejad B, Ghaznavi-Rad E. High Frequency of Ventilator Associated Pneumonia Nosocomial Co-Infection Causedby Methicillin Resistant Staphylococcusaureus and Carbapenem Resistant Acinetobacter baumannii in Intensive Care Unit. jicr. 2015; 1 (2) :67-71
Abstract:   (1180 Views)

Introduction: Ventilator Associated Pneumonia (VAP) is one of the most common nosocomial infections in the intensive care unit and leads to increase of mortality in affected patients. VAP infections occur mainly due to inadequate antibiotic treatment for multi drug-resistant (MDR) pathogens. The aim of this study was to identify the etiologic agents of VAP infections in intensive care unit and antibiotic susceptibility determination of isolated bacteria.

Methods: Overall, 179 respiratory secretions were collected from patients with VAP in vali-Asr hospital, Arak, Iran from October 2013 to November 2014. The samples were cultured in the laboratory culture media, their susceptibility tests were performed, andresultswereinterpretedaccordingtoCLSI guidelines.

Presence of mecA and Sa442 genes in Staphylococcus aureus and oxA-51like gene of Acinetobacterbaumannii isolates separately were analyzed by PCR.

Results: Overall, 169 (90%) of respiratory specimens showed positive culture. The most common isolated pathogen was A. baumanniifollowed by S. aureus. Ninety five percent of A. baumanniiwere resistant to imipenem and 71% of S. aureus isolates were methicillin resistance S. aureus (MRSA).

Conclusion: The elevated prevalence of VAP noscomial infection is alarming.  Emergence of highly resistant isolates is another burden. Therefore, antibiotic prescription policy must be revised. 

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Type of Study: Research | Subject: Special
Received: 2015/10/25 | Accepted: 2015/10/25 | Published: 2015/10/25

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